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SUMMARY:Malaria Mosquito Genomics Across Africa - Dr Mara Lawniczak\, Seni
 or Group Leader\, Wellcome Sanger Institute
DTSTART:20250428T183000Z
DTEND:20250428T200000Z
UID:TALK230242@talks.cam.ac.uk
CONTACT:John Cook
DESCRIPTION:Malaria is a preventable treatable infectious disease but stil
 l it kills up to 600\,000 people each year\, primarily children under the 
 age of five. The disease is caused by a single celled parasitic organism t
 hat is only transmitted between humans by Anopheles mosquitoes. If the mos
 quitoes that transmit the parasite were eliminated or prevented from trans
 mitting\, malaria would end. Gaining a deeper understanding of Anopheles m
 alaria mosquitoes is an especially important undertaking in Africa\, where
  the vast majority of malaria deaths occur and where there are many specie
 s contributing to the disease burden. Among these\, four are considered ma
 jor malaria vectors\, probably accounting for more than 95% of transmissio
 n. This talk will present several different genomic approaches we are taki
 ng to thoroughly characterise Anopheles mosquitoes. These include amplicon
  panels to understand mosquito species diversity and distributions\, short
  read sequencing to glean a comprehensive understanding of population stru
 cture and selection\, and long read sequencing to peek into rapidly diverg
 ing regions of the genome that short reads cannot offer resolution for. Th
 is talk will discuss what we have learned to date and how this contributes
  to malaria control.\n\nMore details "here":https://www.csar.org.uk/lectur
 es/2024-2025/malaria-mosquito-genomics-across-africa_20250428/.
LOCATION:Location: Wolfson Lecture Theatre\, Churchill College\, and Zoom
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