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SUMMARY:The role of astrocyte subtypes in brain function and dysfunction -
  Dr. Philip Hasel\, UK DRI\, Edinburgh University
DTSTART:20250529T110000Z
DTEND:20250529T120000Z
UID:TALK232459@talks.cam.ac.uk
CONTACT:Lucy Theobald
DESCRIPTION:Astrocytes perform critical homeostatic support functions in t
 he central nervous system. It is now clear that astrocytes\, similar to ne
 urons\, can molecularly\, morphologically and functionally specialize to b
 rain areas\, circuits and other anatomical domains. We have recently disco
 vered that astrocytes forming brain barriers in the brain and spinal cord\
 , called glia limitans astrocytes\, are highly specialized. These astrocyt
 es have a highly unusual morphology\, a unique gene expression profile and
  are conserved from fish to mouse to human. Our lab now studies the develo
 pment\, function and dysfunction of these cells using -omics\, imaging and
  transgenic approaches to discovery their role in protecting the brain fro
 m peripheral insults\, injury and neuroinflammation.\n\n---\nPhilip comple
 ted his PhD at Edinburgh University before joining Shane Liddelow’s lab 
 at NYU as a postdoc. There\, he applied -omics approaches to describe new 
 subtypes of astrocytes in the brain and spinal cord. He recently joined th
 e UK Dementia Research Institute in Edinburgh as a Group Leader on a Wellc
 ome Trust Career Development Award to study the role of specialized astroc
 ytes in brain function and dysfunction.\n---\nA Department of Clinical Neu
 rosciences Seminar
LOCATION:Clifford Allbutt Building Lecture Theatre\, Cambridge Biomedical 
 Campus
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