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SUMMARY:Digital twins of the retina as a model for cancer - Simon Walker-S
 amuel (University College London)
DTSTART:20250919T103000Z
DTEND:20250919T105000Z
UID:TALK235210@talks.cam.ac.uk
DESCRIPTION:Digital twins can offer personalised models of human tissue by
  combining imaging data with advanced computational methods. In this talk\
 , I will describe our efforts to build digital twins of the retina\, captu
 ring the structure and function of its vascular networks and how these cha
 nge in disease. By using deep generative learning\, we can personalise the
 se models to individual patients\, even when imaging data are limited\, cr
 eating simulations that reflect patient-specific anatomy and physiology. T
 he retina is particularly valuable as a testbed as pathological angiogenes
 is in diabetic retinopathy shares many features with the abnormal blood ve
 ssel growth seen in cancer. This makes retinal digital twins a powerful pr
 ototype for understanding cancer angiogenesis and for developing new appro
 aches to predicting treatment response.
LOCATION:Seminar Room 1\, Newton Institute
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