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SUMMARY:Evolution of germ-line restricted and unrestricted genomes in dipt
 era - Kamil Jaron\, Sanger Institute
DTSTART:20251113T130000Z
DTEND:20251113T140000Z
UID:TALK235519@talks.cam.ac.uk
CONTACT:131500
DESCRIPTION:Flies show a remarkable diversity of ways genomes are organise
 d. From rapidly inverting genomes of some of the Drosophilidae species\, t
 o remarkably stable genomes of phantom craneflies. We have analysed a data
 set of 340 chromosomal level assemblies to map this diversity and characte
 rise the mode of evolutionary change in genomes of Diptera. Contrary to co
 mmon believe\, the notorious Muller elements do not represent the ancestra
 l linkage groups\, they are a derived karyotype that evolved in the common
  ancestor of Schizophora and hoverflies. Using the ancestral linkage group
  reconstruction as the framework\, we characterised sex chromosome evoluti
 on too. The ancestral dipteran X chromosome is a gene-poor chromosome that
  varies in size many fold across dipteran species\, showing signatures mor
 e typical for B-chromosomes or Y chromosomes. This is at a sharp contrast 
 to germ-line restricted chromosomes found in dark-winged fungus gnats. We 
 have sequenced pool of testes of three species and reconstructed for the f
 irst time germ-line restricted chromosomes on chromosomal level. The chrom
 osomes are found in haploid state in male germline and were thought to be 
 parasitic and likely non-recombining. Despite that\, we showed they are de
 pleted of repeats and show thousands of gene models. This talk will focus 
 on covering the diversity of dipteran genomes and try to phrase well how i
 s that contradicting our expectations.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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