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SUMMARY:Beak to Bedside - Understanding and controlling Campylobacter - An
 drew Grant - University of Cambridge
DTSTART:20251211T150000Z
DTEND:20251211T160000Z
UID:TALK235573@talks.cam.ac.uk
CONTACT:90994
DESCRIPTION:Dr Andrew Grant is an Associate Professor in Microbial Pathoge
 nesis in the Department of Veterinary Medicine\, University of Cambridge. 
 Andrew obtained his BSc degree in Biochemistry and Pharmacology and a PhD 
 in Molecular Microbiology at Southampton University and then moved to the 
 University of Cambridge to a postdoctoral position. After a series of post
 doctoral positions\, studying different enteric bacterial pathogens\, he m
 oved into his current position where his group uses genomic and functional
  genomic approaches\, combined with molecular\, proteomic and imaging tech
 niques\, to determine the basis by which bacterial pathogens survive in di
 fferent environments\, colonise their hosts and cause disease. Andrew is a
 lso a HEI partner of Quadram Institute Bioscience supporting the Instituti
 onal Strategic Programme on Microbes in the Food Chain. Through the differ
 ent research themes the aim is to translate the findings into novel interv
 ention strategies\, including small-molecule therapeutics\, antibodies\, a
 ntimicrobial peptides and vaccines.\n\nCampylobacter is the most common ba
 cterial cause of human gastroenteritis in the world. An acute infection ca
 n have serious long-term consequences\, including Guillain-Barré syndrome
 \, reactive arthritis and irritable bowel syndrome. Campylobacter is commo
 nly found in the gastrointestinal tracts of animals destined for human con
 sumption\, with faecal contamination of meat\, especially chicken\, during
  processing a route of transmission to humans. In the UK\, Campylobacter i
 nfections are estimated to affect 1% of the population and cost the econom
 y ~£1 billion each year. The ability of Campylobacter to colonise and sur
 vive in many animal species and habitats makes them extremely difficult to
  control\, and infection in humans remains difficult to prevent. There are
  no vaccines for animals or humans. Worldwide there has been a rapid incre
 ase in antimicrobial resistant Campylobacter strains\, making them a serio
 us and growing public health threat. There is a need to understand how Cam
 pylobacter survives in different environments\, colonises chickens (and ot
 her animals) and causes disease in humans\, and to use this knowledge to d
 evelop intervention strategies.\n\nIn the talk “Beak to Bedside – Unde
 rstanding and controlling Campylobacter”\, Andrew’s presentation will 
 cover recent and ongoing studies by his group focused on different aspects
  of Campylobacter growth\, survival and intervention.\n
LOCATION:Jean Thomas Lecture theatre\, Sanger Building\, Tennis Court Road
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