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SUMMARY:The Fruit Fly Connectome and Beyond - Yijie Yin\; Saeyeon Kwon
DTSTART:20250916T121500Z
DTEND:20250916T114500Z
UID:TALK236167@talks.cam.ac.uk
CONTACT:124819
DESCRIPTION:Comprehensive synaptic neural wiring diagrams (one form of con
 nectome) of the central nervous system are becoming available for many mod
 el organisms. Here\, we focus on the connectome of an adult fruit fly. We 
 first introduce several datasets presented in Dorkenwald et al. (2024) and
  Schlegel et al. (2024). We then present a study by Pospisil et al. (2024)
 \, The fly connectome reveals a path to the effectome. This paper presents
  a new experimental and statistical framework based on instrumental variab
 les\, that combines whole-brain connectomic data with optogenetic perturba
 tions to infer the effectome - a causal model of how neurons in the fly br
 ain influence one another.\n\n\nPapers:\n\nhttps://www.nature.com/articles
 /s41586-024-07558-y\n\nhttps://www.nature.com/articles/s41586-024-07686-5\
 n\nhttps://www.nature.com/articles/s41586-024-07982-0
LOCATION:CBL Seminar Room\, Engineering Department\, 4th floor Baker build
 ing
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