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SUMMARY:The role of mitochondrial transcriptional processes in modulating 
 human health and disease - Dr Alan Hodgkinson\, King's College London
DTSTART:20250924T140000Z
DTEND:20250924T150000Z
UID:TALK236488@talks.cam.ac.uk
CONTACT:Penny Peck
DESCRIPTION:Mitochondrial dysfunction is implicated in a wide range of hum
 an diseases\, yet its causal role and the reasons for tissue-specific mani
 festations remain poorly understood. Here we show\, using large-scale gene
 tic and transcriptomic data\, that nuclear regulation of mitochondrial gen
 e expression contributes to complex trait biology. Our analyses reveal tis
 sue-dependent mechanisms linking mitochondrial processes to disease risk a
 nd highlight opportunities for understanding and potentially targeting mit
 ochondrial contributions to human health.
LOCATION:MRC MBU\, Level 7 Lecture Theatre\, The Keith Peters Building\, C
 B2 0XY
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