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SUMMARY:Roser Vento-Tormo\, Group leader\, Sanger Institute - Roser Vento-
 Tormo\, Group leader\, Sanger Institute\, Cambridge
DTSTART:20260416T150000Z
DTEND:20260416T160000Z
UID:TALK237070@talks.cam.ac.uk
CONTACT:Liat Churley
DESCRIPTION:This Cambridge Immunology Network Seminar will take place on *
 Thursday 16 April 2026*\, starting at *4:00pm*\, in the Ground Floor Lectu
 re Theatre\, Jeffrey Cheah Biomedical Centre (JCBC)\n\n*Speaker*: Roser Ve
 nto-Tormo\, Group leader in Cellular Genomics\, Wellcome Sanger Institute\
 , Cambridge \n\n*Title*: “Tissue biology through the lens of women’s h
 ealth“\n\n*Abstract*: Female reproductive tissues are central to women
 ’s health\, with roles far beyond reproduction\, yet they have long been
  understudied at the cellular and molecular level. Using single-cell and s
 patial technologies combined with novel computational tools\, our team is 
 decoding the cellular organisation of these tissues. We have redefined imm
 une cells as active regulators of tissue function and gynaecological disea
 se\; identified progenitors and supporting cells across the ovaries\, fall
 opian tubes\, and uterus\; and revealed hidden stromal signalling gradient
 s that compartmentalise tissues and guide their formation and function. Us
 ing cellular atlases as a reference\, my team has pioneered the benchmarki
 ng and improvement of  in vitro models that faithfully mimic human tissues
 \, including reproductive organoid systems and scalable platforms to study
  immune function. Together\, these advances are reshaping female biology i
 nto a predictive\, model-driven science and opening new paths toward trans
 formative solutions for women’s health.\n\n*Bio*: Dr Roser Vento-Tormo i
 s a Group Leader in the Cellular Genomics Programme at the Wellcome Sanger
  Institute in Cambridge\, UK. Established in 2019\, her lab (https://vento
 lab.org/) is dedicated to understanding how gene circuits regulate cell id
 entity and how the tissue microenvironment rewires them\, in the context o
 f reproductive tissues and immunity. They have systematically applied sing
 le-cell and spatial genomics to reproductive tissues across the lifespan\,
  and developed computational and experimental frameworks to interpret data
  and functionally validate predictions. This work has elucidated how repro
 ductive tissues are formed during development\, how their constituent cell
 s interact and remodel during the menstrual cycle\, and how these processe
 s are disrupted in diseases that disproportionately affect women. Roser ha
 s trained numerous PhD students and postdocs\, three of whom are now group
  leaders\, and is a co-ordinator of the Reproductive Bionetwork of the Hum
 an Cell Atlas. She has attracted highly competitive funding (for example f
 rom ERC\, MRC\, NIH\, CZI\, Wellcome-LEAP) and has been recognised by nume
 rous awards including the Early Career Research Award from the Biochemistr
 y Society (2021) and the Foulkes Foundation Prize (2025).\n\n*Host*: Dr Vi
 rginia Pedicord\, CITIID\, Cambridge\n\nRefreshments will be available fol
 lowing the seminar.\n
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
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