BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Talks.cam//talks.cam.ac.uk// X-WR-CALNAME:Talks.cam BEGIN:VEVENT SUMMARY:Epigenome maintenance in response to DNA damage - Sophie Polo\, Gr oup Leader\, Center for Epigenetics and Cell Fate (CEDC)\, CNRS/ Paris Did erot University DTSTART:20251117T140000Z DTEND:20251117T150000Z UID:TALK239065@talks.cam.ac.uk CONTACT:131371 DESCRIPTION:Host: Ritwick Sawarkar\n\nSophie Polo graduated from the Ecole Normale Supérieure de Paris\, France in 2002. She received her PhD in 20 06 working with Geneviève Almouzni at the Curie Institute in Paris\, Fran ce on the role of chromatin assembly factors in cell proliferation and gen ome stability. She then joined Steve Jackson’s laboratory at the Gurdon Institute in Cambridge\, UK for her postdoctoral studies. There\, she deve loped an interest in the response to DNA breaks and characterized the func tion of chromatin remodelers in this context. Back in France\, she obtaine d a permanent staff scientist position in 2011\, and she was awarded the O lga Sain prize from la Ligue contre le Cancer in the same year. Sophie est ablished her own group at the Epigenetics and Cell Fate Centre in 2013 at Paris Diderot University\, with the support of a young investigator progra m from the French National Research Agency\, followed by Starting and Cons olidator Grants from the European Research Council. Sophie was selected EM BO Young Investigator in 2017 and promoted research director in 2018.\nSop hie Polo has been leading the Epigenome integrity group in Paris for the p ast 12 years. She has a long-standing expertise in studying the interplay between chromatin plasticity and genome integrity. Research in her laborat ory combines cutting-edge imaging technologies with proteomics and next-ge neration sequencing to decipher how genome and epigenome maintenance are c oordinated in mammalian cells challenged by genotoxic stress.\n LOCATION:Seminar Room\, Gleeson Building\, MRC Toxicology Unit\, Tennis Co urt Road END:VEVENT END:VCALENDAR