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SUMMARY:Small RNAs in Genome Defence and Beyond - Greg Hannon\, Cancer Res
 earch UK
DTSTART:20251117T173000Z
DTEND:20251117T190000Z
UID:TALK240064@talks.cam.ac.uk
CONTACT:Lawrence Ng
DESCRIPTION:Greg Hannon is recognized for his contributions to small RNA b
 iology\, cancer biology\, and mammalian genomics.  He has a long history i
 n discovery of cancer genes\, beginning with work that led to the identifi
 cation of CDK inhibitors and their links to cancer.  More recently\, his w
 ork has focused on small RNA biology\, which led to an understanding of th
 e biochemical mechanisms and biological functions of RNAi.  He has develop
 ed widely used tools and strategies for manipulation of gene expression in
  mammalian cells and animals and has generated genome-wide shRNA libraries
  that are available to the cancer community and was among the first to dem
 onstrate roles for miRNAs in cancer.  His laboratory also discovered the p
 iRNA pathway and linked this to transposon repression and the protection o
 f germ cell genomes.  He has a continuous history of collaboration and tec
 hnological innovation\, including the development of selective re-sequenci
 ng strategies\, broadly termed exome capture.
LOCATION:Department of Chemistry (Pfizer lecture theatre)
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