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SUMMARY:Computational Ethology for Disease Modelling and Drug Screening - 
 Andre Brown\, Imperial College London
DTSTART:20251201T173000Z
DTEND:20251201T190000Z
UID:TALK240067@talks.cam.ac.uk
CONTACT:Lawrence Ng
DESCRIPTION:Sometimes the best way to study a drug or microbe is just to s
 ee what it does to an animal. However\, measuring and analysing whole-anim
 al responses can be a major bottleneck. We have developed megapixel camera
  arrays to record all the wells of 96-well plates with enough resolution f
 or detailed tracking. We use this approach to measure behavioural profiles
  of C. elegans in 10k conditions per day. Computational ethology at this s
 cale opens new directions in disease modelling and drug screening.  I will
  discuss our work using this approach to find neuroactive natural products
 \, predict the mode of action of insecticides from behaviour\, and to mode
 l dozens of genetic diseases.\n
LOCATION:Department of Chemistry (Pfizer lecture theatre)
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