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SUMMARY:Keeping mitochondria in shape: a matter of life and death - Profes
 sor Luca Scorrano\, University of Padua
DTSTART:20251203T150000Z
DTEND:20251203T160000Z
UID:TALK240454@talks.cam.ac.uk
CONTACT:Penny Peck
DESCRIPTION:Over the past two decades\, alterations in mitochondrial ultra
 structure and morphology\, as well as the interactions between mitochondri
 a and other cellular organelles\, have been increasingly recognized as key
  regulators of numerous physiological and pathological processes\, includi
 ng apoptosis\, inflammation\, differentiation\, and tumorigenesis. Despite
  these advances\, the precise role of mitochondrial dynamics and organelle
  interactions in orchestrating complex cellular responses\, both under phy
 siological conditions and in the face of reversible or irreversible cellul
 ar damage\, remains incompletely understood. We will discuss key experimen
 ts that illuminated the contribution of mitochondrial shape\, ultrastructu
 re\, and inter-organelle communication to cell physiology and disease. We 
 will also present our recent work aimed at identifying the unresolved ques
 tions in the field of mitochondrial dynamics and contact sites regulation.
LOCATION:MRC MBU\, Level 7 Lecture Theatre\, The Keith Peters Building\, C
 B2 0XY
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