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SUMMARY:Unattended working memory items are coded by persistent activity i
 n human medial temporal lobe neurons - Julie de Falco
DTSTART:20251031T140000Z
DTEND:20251031T150000Z
UID:TALK240496@talks.cam.ac.uk
CONTACT:Adam Triabhall
DESCRIPTION:This week we will discuss and debate a very recent paper by Pa
 luch and colleagues (2025).\n\nAbstract: “The role of persistent neural 
 activity in working memory storage is well documented\, particularly in ta
 sks where memorized items are of equal importance. However\, the encoding 
 mechanism for unattended items\, often considered as ‘activity silent’
 \, remains poorly understood. Here we recorded the activity of image-selec
 tive neurons in the medial temporal lobe while subjects (n = 12) shift
 ed attention between concurrently stored memory items. Our results demonst
 rate that both attended and unattended memory items are encoded through pe
 rsistent activity. Additionally\, we observed a dynamic transformation in 
 the neuronal subspace following cue presentation\, reflecting a shift in h
 ow information was maintained. While information about the unattended item
  was decodable at the single-trial level from preselected image-selective 
 cells\, it was not decodable from the entire population of medial temporal
  lobe cells. These findings support models of persistent activity and chal
 lenge the notion that unattended items are stored via ‘activity-silent
 ’ mechanisms” (Paluch et al.\, 2025).\n\nReference: Paluch\, K.\, Magn
 uski\, M.\, Średniawa\, W.\, Ivanovski\, D.\, Rysz\, A.\, Służewska-Nie
 dźwiedź\, M.\, Pasterski\, T.\, Fortuna\, W.\, Smarzewska\, K.\, Reinach
 er\, P. C.\, Kaczor\, S.\, Tabakow\, P.\, Babu\, H.\, & Kamiński\, J. (20
 25). Unattended working memory items are coded by persistent activity in h
 uman medial temporal lobe neurons. Nature Human Behaviour. https://doi.org
 /10.1038/s41562-025-02235-0
LOCATION:https://cam-ac-uk.zoom.us/j/92612577704?pwd=MUtqMjVQdXNmUTVIYjRkM
 G1NUW9GZz09
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