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SUMMARY:Rewiring Rhythms: Restoring Metastable Brain Dynamics for Neuroreh
 abilitation - Wael El-deredy (Universitat de València)
DTSTART:20251202T101500Z
DTEND:20251202T110000Z
UID:TALK240976@talks.cam.ac.uk
DESCRIPTION:We treat the brain as multistate\, metastable dynamical system
 \, continuously transitioning between quasistable attractors that support 
 perception\, cognition\, and action. Neurological injury and disease disru
 pt the dynamics\, leading to the loss of functional states and the emergen
 ce of maladaptive patterns. Neurorehabilitation\, from this perspective\, 
 can be understood not just as repairing damaged circuits but as reshaping 
 brain dynamics&mdash\;nudging neural activity toward favorable attractor s
 tates and restoring the system&rsquo\;s capacity for flexible metastabilit
 y.\nIn this talk\, we will outline how concepts from dynamical systems the
 ory\, control\, and network neuroscience provide a framework for understan
 ding the principles of recovery\, and will show how external interventions
  (stimulation\, rhythmic entrainment\, sensory feedback\, and training) ca
 n act as targeted perturbations that reconfigure trajectories of brain act
 ivity. &nbsp\;We will show examples from both experimental studies and com
 putational models will illustrate how recovery can be seen as a process of
  re-establishing the fluid repertoire of brain states rather than returnin
 g to a single &ldquo\;normal&rdquo\; configuration. By adopting this dynam
 ic viewpoint\, neurorehabilitation becomes a problem of guiding a complex 
 system back to health&mdash\;through rhythm\, resonance\, and controlled i
 nstability&mdash\;opening new avenues for personalized and adaptive therap
 eutic strategies.
LOCATION:Seminar Room 1\, Newton Institute
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