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SUMMARY:Dated gene duplications elucidate the evolutionary assembly of the
  eukaryotic cell - Christopher Kay\, University of Bristol
DTSTART:20260204T160000Z
DTEND:20260204T170000Z
UID:TALK243523@talks.cam.ac.uk
CONTACT:Selen Etingü
DESCRIPTION:The origin of eukaryotes is one of the major transitions in li
 fe’s history\, yet the timeline of how the eukaryotic cell was assembled
  remains surprisingly unclear. Both fossils and molecular clocks give broa
 d ranges\, making it difficult to tell whether eukaryogenesis was a sudden
  event or a long\, staged process. In this talk\, I will present a differe
 nt line of evidence based on the order of gene duplications across key cel
 lular systems. By linking duplicated genes to specific intracellular featu
 res\, we can reconstruct the sequence in which cytoskeletal components\, m
 embrane-trafficking systems\, and metabolic innovations emerged. Time-reso
 lving these duplications also allows us to frame eukaryogenesis within the
  palaeo-environmental conditions of early Earth.\nThe resulting picture su
 pports a protracted\, stepwise assembly of eukaryotes — beginning before
  the widespread rise of oxygen.\n
LOCATION:Martin Ryle Seminar Room\, Kavli Institute
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