BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:How Cells Make Membrane Proteins - Manu Hegde\, MRC LMB Group Lead
 er
DTSTART:20260202T173000Z
DTEND:20260202T190000Z
UID:TALK244162@talks.cam.ac.uk
CONTACT:Lawrence Ng
DESCRIPTION:Your genome encodes ~5000 proteins that are embedded in the me
 mbranes of your cells. Membrane-embedded proteins are the conduits through
  which information and materials are exchanged between the cell and its en
 vironment. Examples of membrane proteins include ion channels\, hormone re
 ceptors\, nutrient transporters\, cell adhesion proteins\, and many more. 
 They control nearly everything – neurotransmission\, immunity\, sight\, 
 hearing\, touch\, digestion\, taste\, etc. – and problems in making them
  correctly underly diseases such as retinal degeneration and cystic fibros
 is. Our research aims to provide a detailed molecular explanation for thes
 e complicated and diverse set of proteins get embedded into a membrane and
  folded into a functional product. I will discuss how we discovered the sp
 ecialised machinery involved in membrane protein biogenesis\, and our ongo
 ing efforts to understand how this machinery works.\n\nShort Biography: Ra
 manujan Hegde is a Programme Leader and Head of the Cell Biology Division 
 at the MRC Laboratory of Molecular Biology (LMB)\, Cambridge. His research
  focuses on the maturation and quality control of newly made proteins in c
 ells. Hegde completed his undergraduate studies at the University of Chica
 go and his MD and PhD at the University of California\, San Francisco. He 
 then led a research group at the US National Institutes of Health from 199
 9 to 2011\, then moved to the LMB in Cambridge. Hegde’s work has been re
 cognized by several honours\, including his election as a member of the Eu
 ropean Molecular Biology Organization\, a Fellow of the Royal Society\, an
 d a Fellow at Trinity College\, Cambridge.
LOCATION:Department of Chemistry (Pfizer lecture theatre)
END:VEVENT
END:VCALENDAR