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SUMMARY:Causal effect interpretation in Mendelian randomization studies - 
 Eleanor Sanderson (University of Bristol)
DTSTART:20260304T140000Z
DTEND:20260304T144500Z
UID:TALK244396@talks.cam.ac.uk
DESCRIPTION:Mendelian randomization is an approach to causal inference tha
 t uses genetic variants as instrumental variables to estimate causal effec
 ts. Although often applied with a single exposure and outcome Mendelian ra
 ndomization has been extended to consider models including multiple traits
 . The estimates obtained are usually interpreted as &lsquo\;lifetime&rsquo
 \; effects of the exposure on the outcome. In this talk I will consider th
 is definition and what it means in applications of Mendelian randomization
  in two settings\; when the exposure(s) are time varying and when there ar
 e multiple potential exposure traits which have a highly correlated geneti
 c structure.&nbsp\;
LOCATION:Seminar Room 1\, Newton Institute
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