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SUMMARY:Neural correlates of probabilistic decision making in S1 during vi
 rtual reality navigation - Alex George Armstrong\, University of Illinois 
 Urbana Champaign
DTSTART:20260407T110000Z
DTEND:20260407T120000Z
UID:TALK246010@talks.cam.ac.uk
CONTACT:Keita Tamura
DESCRIPTION:Abstract\n\nUtilising tactile VR to harness ethologically rele
 vant whisker-guided navigation behaviour in mice reveals striking decision
  related signals in the early cortical hierarchy. Large-scale Neuropixel r
 ecordings and optical perturbation experiments show these signals in S2 ar
 e fed back into S1 to fundamentally change how sensory information is proc
 essed during salient decision making.\n\n\nReferences\n\nArmstrong\, A.G. 
 & Vlasov\, Y.  Neural correlates of perceptual decision making in primary 
 somatosensory cortex. BioRxiv https://doi.org/10.1101/2025.03.29.646003\n\
 nArmstrong\, A.G. & Vlasov\, Y. (2026) Probabilistic perceptual decision-m
 aking during whisker-guided navigation causally depends on a single cortic
 al barrel column. Journal of Neuroscience https://doi.org/10.1523/JNEUROSC
 I.0930-25.2026\n\nAkritas\, M\, Armstrong\, A.G. et al. (2024) Nonlinear s
 ensitivity to acoustic context is a stable feature of neuronal responses t
 o complex sounds in auditory cortex of awake mice. eLife 13:RP98415. https
 ://doi.org/10.7554/eLife.98415.1\n\nArmstrong\, A.G. et al. (2022) Compres
 sion and amplification algorithms in hearing aids impair the selectivity o
 f neural responses to speech. Nature Biomedical Engineering 6:717–73.  h
 ttps://doi.org/10.1038/s41551-021-00707-y
LOCATION:Bryan Matthews Seminar Room\, Physiological Laboratory building\,
  Department of Physiology\, Development and Neuroscience
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