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SUMMARY:Computational Neuroscience Journal Club - Dr. Gergo Orban (Univers
 ity of Cambridge)
DTSTART:20100518T150000Z
DTEND:20100518T160000Z
UID:TALK24938@talks.cam.ac.uk
CONTACT:Prof Máté Lengyel
DESCRIPTION:Gergő Orbán presents\n\nEcker AS\, Berens P\, Keliris GA\, B
 ethge M\, Logothetis NK\, Tolias AS\n\n*Decorrelated neuronal firing in co
 rtical microcircuits*\n\n_Science_ 327:584-7\, 2010\n\nThe paper is availa
 ble at http://www.sciencemag.org/cgi/content/full/327/5965/584\n\nAbstract
 :\n\nCorrelated trial-to-trial variability in the activity of cortical neu
 rons is thought to reflect the functional connectivity of the circuit. Man
 y cortical areas are organized into functional columns\, in which neurons 
 are believed to be densely connected and to share common input. Numerous s
 tudies report a high degree of correlated variability between nearby cells
 . We developed chronically implanted multitetrode arrays offering unpreced
 ented recording quality to reexamine this question in the primary visual c
 ortex of awake macaques. We found that even nearby neurons with similar or
 ientation tuning show virtually no correlated variability. Our findings su
 ggest a refinement of current models of cortical microcircuit architecture
  and function: Either adjacent neurons share only a few percent of their i
 nputs or\, alternatively\, their activity is actively decorrelated.\n
LOCATION:Cambridge University Engineering Department\, CBL Rm #438 (http:/
 /learning.eng.cam.ac.uk/Public/Directions)
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