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SUMMARY:Protein Mechanics - Alexander MacDonald (CUED - Research Student\,
  Structures Group)
DTSTART:20100604T140000Z
DTEND:20100604T150000Z
UID:TALK25134@talks.cam.ac.uk
CONTACT:Katerina Ondrova
DESCRIPTION:    Proteins undertake a variety of uses within our bodies und
 ertaking structural\, signalling\, catalysis and transportation functions.
   Some proteins display intriguing mechanical properties (spider silk) whi
 le protein malfunction/accumulation has serious implications for disease (
 Creutzfeldt-Jakob disease and Alzheimer's).  While the importance of under
 standing protein operation has resulted in a protein modelling explosion\,
  no tool has proven to be especially effective in elucidating protein func
 tion over larger time scales (milliseconds and seconds).\n\n   This talk w
 ill discuss the extension of structural mechanics methods for the analysis
  of pin-jointed structures to illuminate the operational mechanism of prot
 eins.  Whilst providing a novel and consistent approach\, this tool also u
 nifies some disparate methods currently utilised by biologists.
LOCATION:Engineering Department - **LR3A**
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