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SUMMARY:The long and the short of it: dez implicates Zn homeostasis in sko
 tomorphogenesis - Mike Haydon\, Alex Webb group
DTSTART:20101126T130000Z
DTEND:20101126T133000Z
UID:TALK26675@talks.cam.ac.uk
CONTACT:15560
DESCRIPTION:Micronutrients such as zinc (Zn) and iron (Fe) are essential f
 or normal plant growth but are toxic to cells when present in excess. Ther
 efore\, metal homeostasis networks exist to ensure optimal concentration o
 f these elements while maintaining the availability of the free ions below
  toxicity thresholds. This involves coordinated regulation of metal transp
 ort proteins and chelating molecules. To identify regulatory mechanisms of
  metal homeostasis in plants\, a forward genetic screen was used to identi
 fy mutations that disrupt up-regulation of ZINC-INDUCED FACILITATOR1 (ZIF1
 )\, a vacuolar nicotianamine transporter\, by Zn. Several novel mutants we
 re identified\, including de-etiolated by Zn (dez) which has a photomorpho
 genic phenotype when grown in the dark on media containing high Zn. Phenot
 ypic and microarray analysis implicated phytohormones and indicates that r
 egulation of metal homeostasis is important for skotomorphogensis.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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