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SUMMARY:Why is Genomics so unfashionable in Drug Discovery? - Quin Wills (
 SimuGen)
DTSTART:20101013T130000Z
DTEND:20101013T140000Z
UID:TALK27343@talks.cam.ac.uk
CONTACT:Danielle Stretch
DESCRIPTION:The pharmaceutical industry is experiencing a significant inno
 vation crisis.\nIt would seem that the era of 'big hit' drugs\, science dr
 iven by\nhigh-throughput chemistry and pharmaceutical companies is nearing
  an end\,\nwith most major drug patents expiring within two years. Only ju
 st a few\nyears ago there was enormous excitement around how functional ge
 nomics and\nother 'high resolution' technologies would allow systems biolo
 gy to\nreinvigorate drug R&D. These days we see a large return to traditio
 nal\nmethods\, amidst complaints that omics hasn't truly helped make any d
 ecisions\nbut just added to the data burden.\n\nThe talk will be a general
  discussion on current drug discovery trends\, 'big\ndata' approaches\, 'o
 pen-source' biology\, where the problems are\, and\nsuggested solutions. A
 s a case study\, we will use toxicogenomics software\nand models developed
  in-house at SimuGen\, a pharmacogenomics company born at\nCCBI.\n\n\n
LOCATION:Centre for Mathematical Sciences\, Meeting Room 4
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