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SUMMARY:Why is genomics now unfashionable in drug discovery? - Quin Wills 
 (SimuGen)
DTSTART:20101013T130000Z
DTEND:20101013T140000Z
UID:TALK27353@talks.cam.ac.uk
CONTACT:Danielle Stretch
DESCRIPTION:The pharmaceutical industry is experiencing a significant inno
 vation\ncrisis.  It would seem that the era of 'big hit' drugs\, science d
 riven\nby high-throughput chemistry and pharmaceutical companies is nearin
 g\nan end\, with most major drug patents expiring within two years. Only\n
 just a few years ago there was enormous excitement around how\nfunctional 
 genomics and other 'high resolution' technologies would\nallow systems bio
 logy to reinvigorate drug R&D. These days we see a\nlarge return to tradit
 ional methods\, amidst complaints that omics\nhasn't truly helped make any
  decisions but just added to the data\nburden.\n\nThe talk will be a gener
 al discussion on current drug discovery\ntrends\, 'big data' approaches\, 
 'open-source' biology\, where the\nproblems are\, and suggested solutions.
  As a case study\, we will use\ntoxicogenomics software and models develop
 ed in-house at SimuGen\, a\npharmacogenomics company born at CCBI.\n
LOCATION:MR4\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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