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SUMMARY:'Modelling and analysis of diabetes-related metabolic processes' -
  Dr John Hancock\, MRC Harwell
DTSTART:20101208T150000Z
DTEND:20101208T160000Z
UID:TALK28394@talks.cam.ac.uk
CONTACT:Penny Peck
DESCRIPTION:The relationship between gene mutations and disease is a compl
 ex one. As we acquire more information it is becoming increasingly difficu
 lt for individual biologists to maintain an overview of the structure and 
 function of the systems they work on. To overcome this there is a need for
  computational models that can aid the bench scientist both in the design 
 of experiments and understanding how well current knowledge describes the 
 system at hand. As a first step towards this we have constructed models of
  molecular systems that play a part in Type II diabetes and mitochondrial 
 function. I will present an overview of these models including an analysis
  of the evolution of the core biochemical processes leading from glucose b
 reakdown to ATP production in pancreatic β-cells. 
LOCATION:Sackler Lecture Theatre (Level 7)\, Wellcome Trust/MRC Building\,
  Addenbrooke's Site
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