BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Mechanics and growth of tissues - Jean-Francois Joanny\, Institute
  Curie
DTSTART:20110225T140000Z
DTEND:20110225T150000Z
UID:TALK29252@talks.cam.ac.uk
CONTACT:Erika Eiser
DESCRIPTION:We present a mechanical model to describe the growth of health
 y and cancerous tissues. \n\nWe first show that because of the coupling be
 tween cell division and the local stress\, a tissue can be considered as a
  visco-elastic liquid with a relaxation time smaller than the cell divisio
 n time. We give examples of the liquid behavior related to the competition
  for space between two tissues and discuss the stability of the interface 
 between two tissues. \nWe then present numerical simulations of tissues ba
 sed on  a dissipative particle dynamics algorithm. The simulations confirm
  the liquid-like behavior of the tissue and have been used to study the rh
 eology of the tissue.\nFinally\, we discuss the steady state structure of 
 villis which are the protrusions of the surface of the intestine or the co
 lon. We describe the formation of villis as a buckling instability of a po
 lar cell monolayer. The polarity of the layer does not seem to play a role
  in the intestine where the villis are arranged in a square array but it i
 s important in the colon where they are organized in a hexagonal array.
LOCATION:Pippard Lecture Theatre\, Cavendish Laboratory
END:VEVENT
END:VCALENDAR