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SUMMARY:Real-time measurements of volatile organic compounds by CIR-ToF-MS
  - Dr Iain White\, University of Leicester
DTSTART:20110314T141500Z
DTEND:20110314T151500Z
UID:TALK29346@talks.cam.ac.uk
CONTACT:Dr Alex Archibald
DESCRIPTION:Measurement of volatile organic compounds (VOCs) impacts areas
  as diverse as atmospheric composition and pollution studies\, aroma analy
 sis and medical diagnostics through breath analysis.  Chemical Ionisation 
 Reaction-Time of Flight-Mass Spectrometry (CIR-ToF-MS) is a novel direct m
 ass spectrometric technique that is capable of simultaneously monitoring m
 ultiple VOC species quantitatively and in near real-time.  The CIR-MS tech
 nique (a more general version of proton transfer reaction mass spectrometr
 y (PTR-MS) but utilising alternative chemical ionisation schemes) is based
  upon soft ionisation by a reagent species such as H2O\, NO or O2 and is c
 apable of recording an entire mass spectrum in seconds with sensitivities 
 in the order of 0.1 counts ppbV-1 s-1 in each unit mass channel.\n\nThis t
 echnique has been deployed by the Leicester Atmospheric Chemistry Research
  Group for a number of applications in the analysis of a range of trace at
 mospheric VOCs and oxygenated volatile organic compounds (OVOCs).  For exa
 mple\, in several atmospheric chamber studies it has been applied in gas p
 hase SOA forming systems to measure a variety of globally important aeroso
 l precursors.   In applications such as this\, complex spectra are observe
 d\, the deconvolution of which can be used to track the formation of OVOC 
 products following VOC photo-oxidation and has been used to provide mechan
 istic detail to advance and elucidate atmospheric chemistry models.  In co
 ntrast\, medical diagnoses and prognoses through CIR-MS measurements of br
 eath may be possible using ‘air fingerprinting’ whereby spectra are re
 cognised and compared with a library of breath phenotypes.  These applicat
 ions are discussed along with future directions in quantitative direct MS 
 analysis.\n
LOCATION:Unilever Lecture Theatre\, Department of Chemistry
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