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SUMMARY:“Development and Manufacture of an Affinity Filter for the Remov
 al of vCJD from Blood and Blood-Derived Products” - Dr Steve Burton\, Ch
 ief Exec Officer\, Prometic Biosciences Ltd
DTSTART:20110225T153000Z
DTEND:20110225T163000Z
UID:TALK29888@talks.cam.ac.uk
CONTACT:Elena Gonzalez
DESCRIPTION:Steve will talk about the challenges encountered during the de
 velopment and\nmanufacture of a medical device for the capture and removal
  of infectious prions\nfrom donated blood. The consumption of BSE contamin
 ated beef products in the late\n1980’s and early 1990’s gave rise to a
  new human pathogenic disease – variant\nCreutzfeldt-Jacob Disease (vCJD
 ). This fatal brain wasting disease has a long\nincubation time and can be
  transferred unknowingly from an infected\, but outwardly\nhealthy person\
 , to an uninfected person by blood transfusion.\nThe solution to this thre
 at was to develop a unique blood filter\, P-CAPT® \, a sterile\,\nsingle-
 use medical device which incorporates novel affinity ligand technology and
 \nnovel membrane technology. This has undergone extensive safety and clini
 cal\nstudies and is now in routine use at various locations around the wor
 ld to improve\nblood safety. Materials design and biochemical engineering 
 were employed in the\ndevelopment of this product . The importance of a mu
 ltidisciplinary team approach to\nproblem solving will also be discussed.
LOCATION:Dept Chemical Engineering and Biotechnology\, New Museums Site\, 
 Pembroke Street\, CB2 3RA
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