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SUMMARY:The Female Side of Fertilization: Crystal Structure of Vertebrate 
 Sperm Receptor ZP3 - Luca Jovine\, Karolinska Institute
DTSTART:20110328T151500Z
DTEND:20110328T170000Z
UID:TALK30073@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Species-specific recognition between egg and sperm constitutes
  the initial\, essential step of fertilization. Understanding this event w
 ould increase our knowledge of human infertility and could pave the way to
  the development of novel non-hormonal contraceptives\; however\, despite 
 30 years of very active research\, its molecular basis remains unclear. I 
 will present recent crystal structures of glycoprotein ZP3\, the component
  of the extracellular coat of eggs that acts as sperm receptor\, and discu
 ss what they tell us about the very first moments of conception.
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
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