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SUMMARY:Small RNAs and hybridization in the unicellular green algae\, Chla
 mydomonas reinhardtii - Daisy Hessenberger
DTSTART:20110428T153000Z
DTEND:20110428T160000Z
UID:TALK30676@talks.cam.ac.uk
CONTACT:Suzy Stoodley
DESCRIPTION:When conspecific or closely related populations are crossed\, 
 the ensuing hybridisation can result in unique hybrid phenotypes\, extreme
  in relation to that of the parents. A possible hybrid effect is transgres
 sive segregation\, where heritable quantifiable hybrid traits\, either phe
 notypic or genotypic\, are non-additive or differ significantly from the m
 id-parental value. Recent studies have found trangressive segregation of s
 mall RNA expression in higher plants. In this PhD\, the unicellular green 
 algae Chlamydomonas reinhardtii will be used to investigate the transgress
 ive segregation of small RNA populations and other possible hybrid effects
  on small RNAs. Crosses will be set up between genetically divergent yet c
 onspecific strains to allow comparison between the parental and hybrid gen
 omes. To investigate the mechanism of transgressive segregation\, RNA sile
 ncing mutants and studies of the epigenome will be used. Characterizing hy
 bridisation in C.reinhardtii could provide insight into the function of sm
 all RNAs in unicellular algae and the role of small RNAs in speciation in 
 general.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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