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SUMMARY:The role of cucumber mosaic virus 2b protein in subverting plant d
 efensive signalling pathways - Trisna Tungadi
DTSTART:20110610T123000Z
DTEND:20110610T130000Z
UID:TALK30694@talks.cam.ac.uk
CONTACT:Suzy Stoodley
DESCRIPTION:Cucumber mosaic virus (CMV) is the plant virus with the broade
 st host range. It is transmissible by more than 80 aphid species in a non-
 persistent manner. The CMV genome encodes five proteins\, one of which is 
 the 2b counter-defence protein\, which interferes with host defensive sign
 alling pathways. The ability of the CMV 2b protein to disrupt the host def
 ensive network against CMV infection may influence the virus-plant-vector 
 relationship. Previous work showed that on Nicotiana tabacum (tobacco) pla
 nts that were infected with a CMV mutant unable to produce the 2b protein 
 (CMV∆2b)\, there were lower aphid survival and colony growth compared wi
 th the ones on wild-type CMV infected plants. This suggests that on tobacc
 o\, CMV infection may promote aphid performance. My project focuses on ide
 ntifying CMV gene product(s) that elicit defensive responses in tobacco ag
 ainst aphids. Transgenic tobacco plants and aphids\, Myzus persicae\, are 
 being generated to assess aphid-plant interactions in the presence or abse
 nce of one or more of CMV gene product(s).
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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