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SUMMARY:A primer on DNA origami and why molecular biologists might care - 
 Hendrik Dietz\, TU Munich
DTSTART:20110512T151500Z
DTEND:20110512T170000Z
UID:TALK30725@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Advanced molecular self-assembly with ‘DNA origami’ [1] of
 fers a unique route for building custom shaped high-complexity objects tha
 t are commensurate in size to biological macromolecules. DNA origami objec
 ts can be used as platforms for placing\, orienting\, and even manipulatin
 g biological molecules in user defined ways.Thus\, DNA origami objects can
  not only help improve existing experimental methods in the molecular bios
 ciences but they also open completely new avenues of exploration. \n\nIn o
 ur laboratory we have set out to develop custom “nano’ instrumentation
  based on DNA origami that complements single-molecule-level methods for o
 bserving and manipulating biological macromolecules. Among other goals\, w
 e seek to enable the study of adhesive interactions between biomolecules i
 n unprecedented detail. We also aim to develop tools for unraveling the co
 nformational dynamics of proteins at work in novel ways. More long term\, 
 we hope to be able to create a biologically inspired nanotechnology includ
 ing devices that are capable of performing complex tasks such as enzymatic
  catalysis or molecular transport for human purposes.
LOCATION:Max Perutz Lecture Theatre\, Medical Research Council (MRC) (MRC 
 Laboratory of Molecular Biol
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