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SUMMARY:How cells defend their cytosol against bacterial invasion - Dr Fel
 ix Randow\, MRC-LMB\, Cambridge
DTSTART:20110504T113000Z
DTEND:20110504T123000Z
UID:TALK30771@talks.cam.ac.uk
CONTACT:Sue Griffin
DESCRIPTION:The extracellular immune system commands antibodies and other 
 powerful effector mechanisms\, which are thought to be responsible for the
  hidden lifestyle of intracellular bacteria. Despite the abundance of nutr
 ients in the cytosol most intracellular bacteria live in vesicles\, sugges
 ting cytosolic immunity is equally potent and the vesicular life style the
  path of least resistance for intracellular bacteria. \n\nI will discuss h
 ow cells detect bacteria invading their cytosol\, how such bacteria are ma
 rked with a poly-ubiquitin coat\, and how they are targeted for autophagy.
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis Court Road
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