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SUMMARY:Dissecting mechanisms controlling somatic cell reprogramming - Mar
 ia Pia Cosma\,Unit of Reprogramming and Regeneration\, Centre de Regulacio
 ' Genomica (CRG)\,Barcelona\, Spain
DTSTART:20110606T130000Z
DTEND:20110606T140000Z
UID:TALK31538@talks.cam.ac.uk
CONTACT:Shannon Tinley-Browne
DESCRIPTION:Research Interests: Whether somatic cell reprogramming can occ
 ur in vivo in higher vertebrates and the molecular mechanisms driving repr
 ogramming remain to be defined. Activation of the Wnt/Î²-catenin signall
 ing pathway enhances reprogramming of somatic cells after their fusion wit
 h ESCs. Wnt signalling also controls regeneration in response to damage in
  lower and higher vertebrates. Our main goals is to dissect mechanisms of 
 somatic cell reprogramming and to determine whether activation of Wnt/Î²
 -catenin signalling controls tissue regeneration by enhancing cell fusion-
 mediated reprogramming.
LOCATION:Brain Repair Centre\, Forvie Site\, Robinson Way
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