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SUMMARY:Inferring mechanisms of gene regulation from patterns of evolution
 ary divergence - Itay Tirosh (Weizmann Institute)
DTSTART:20111026T150000Z
DTEND:20111026T160000Z
UID:TALK32027@talks.cam.ac.uk
CONTACT:Florian Markowetz
DESCRIPTION:Evolution of gene expression plays a major role in generating 
 phenotypic diversity and has been studied extensively in recent years. I w
 ill present a comprehensive comparative analysis of gene regulation betwee
 n yeast species and the emerging evolutionary insights. Importantly\, apar
 t from understanding the evolutionary process\, these analyses reveal the 
 dynamics of gene expression and thereby elucidate basic mechanisms and pri
 nciples of gene regulation. I will highlight a hybrid-based approach that 
 is instrumental in these analyses\, and describe the coupling that we rece
 ntly identified with this approach between transcription and mRNA degradat
 ion.\n\n\nNote the date and room change: Wednesday in 215\n\nHosted by Nit
 zan Rosenfeld
LOCATION:Cancer Research UK Cambridge Research Institute\, Room 215
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