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SUMMARY:Regenerative Antioxdant Rare Earth Oxide Nanoparticles - Dr Sudipt
 al Seal
DTSTART:20110711T150000Z
DTEND:20110711T160000Z
UID:TALK32045@talks.cam.ac.uk
CONTACT:Ian Farnan
DESCRIPTION:\nAbstract:\nReactive oxygen and nitrogen species play a criti
 cal role in many degenerative diseases. Nanomaterials\, especially modifie
 d fullerenes and cerium oxide nanoparticles\, have been shown to effective
 ly protect mammalian cells against damage caused by increased reactive oxy
 gen or nitrogen species\, and has been shown to act as effective superoxid
 e dismutase mimetic in vitro. The redox ability of rare earth oxides (ceri
 a\, lanthanides\, etc) has been used in a wide range of applications such 
 as three way catalysis\, oxygen buffer systems\, sensors and corrosion pre
 vention. While these nanostructures have been widely used in many inorgani
 c applications\, their role in biology as catalyst is not explored fully. 
 This presentation will provide a brief overview of the applications of nan
 oceria in treatment of disorders caused by ROS. The role of size and stabi
 lity has also been explored. For various practical applications\, synthesi
 s of biocompatible and stable suspensions of nanoceria is essential. It wa
 s found that the redox kinetics of regenerative ceria nanoparticles can be
  controlled with the type of medium and their implications in nanobiomedic
 ine is presented. (Funding: National Science Foundation NIRT\, National In
 stitute of Health RO1)\n
LOCATION:Harker 2 lecture room\, Department of Earth Sciences\, Downing Si
 te
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