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SUMMARY:Approximation of the individual Fisher information matrix and its 
 use in design of population PK/PD studies - Leonov\, S (GlaxoSmithKline)
DTSTART:20110812T084500Z
DTEND:20110812T093000Z
UID:TALK32335@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:We continue a discussion started at PODE 2010 meeting about di
 fferent types of approximation of the individual Fisher information matrix
  and their use in design of population PK/PD studies which are described b
 y nonlinear mixed effects models. We focus on several Monte Carlo-based op
 tions and provide examples of their performance.\n
LOCATION:Seminar Room 1\, Newton Institute
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