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SUMMARY:An ecological approach to antimicrobial resistance: genes\, hosts\
 , and populations - Dr Alison Mather\, The Wellcome Trust Sanger Institute
DTSTART:20111019T153000Z
DTEND:20111019T163000Z
UID:TALK33026@talks.cam.ac.uk
CONTACT:Suzy Blows
DESCRIPTION:To date\, investigation and policy development relating to ant
 imicrobial\nresistance (AMR) have focused largely on describing patterns o
 f resistance\nto individual antimicrobials\, often from restricted data so
 urces. What this\napproach fails to accommodate is the complexity of AMR\,
  such as genetic\nlinkage of resistance determinants\, which could potenti
 ally lead to\ninaccurate inference. In this presentation\, novel approache
 s to the\nepidemiology of AMR are described\, taking an ecological perspec
 tive and\nexamining several key issues: The relative contribution to AMR f
 rom animal\nand human populations\; the potential differences between acti
 ve and passive\nsurveillance of AMR\; the associations of age\, antimicrob
 ial treatment and a\nshared environment with AMR diversity\; and the relat
 ionships between AMR\nphenotype and genotype. These approaches provide a f
 ramework for similar\nevaluations in other host-pathogen combinations in o
 ther settings\,\nproviding opportunities to develop a richer understanding
  of the\nepidemiology of resistance to inform future policy.
LOCATION:Lecture Theatre 1\, Department of Veterinary Medicine
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