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SUMMARY:Replicating RNA with RNA - Phil Holliger\, LMB
DTSTART:20111122T181500Z
DTEND:20111122T193000Z
UID:TALK33499@talks.cam.ac.uk
CONTACT:Alexey Morgunov
DESCRIPTION:A critical event in the origin of life is thought to have been
  the emergence of an RNA molecule capable of self-replication as well as m
 utation\, and hence evolution towards ever more efficient replication. As 
 this primordial replicase appears to be have been lost in time\, we are us
 ing synthetic biology to build modern-day “Doppelgangers” of the ances
 tral replicase to reconstruct and study life’s first genetic system.\n\n
 I will discuss our progress in the engineering and evolution of an RNA rep
 licase as well as future challenges such as the integration of RNA self-re
 plication within protocellular structures with a view to build simple quas
 icellular systems with life-like properties.
LOCATION:Winstanley Lecture Theatre\, Trinity College
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