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SUMMARY:Effect of prenatal testosterone exposure on language development i
 n early childhood. - Lauren Hollier
DTSTART:20111209T130000Z
DTEND:20111209T140000Z
UID:TALK34733@talks.cam.ac.uk
CONTACT:Amber Ruigrok
DESCRIPTION:Prenatal exposure to testosterone is known to affect fetal bra
 in maturation and later neurocognitive function.  However\, research on th
 e effects of prenatal testosterone exposure has been limited by indirect m
 easures of testosterone (e.g. 2D:4D ratio) and small unrepresentative samp
 les. The aim of this research is to investigate whether circulating fetal 
 testosterone concentrations are associated with language development in ea
 rly childhood\, using umbilical cord serum testosterone as a surrogate mea
 sure of prenatal testosterone exposure in a large unselected birth cohort.
  We hypothesised that higher fetal testosterone concentrations will be inv
 ersely related to spontaneous language ability in early childhood. Umbilic
 al cord serum samples taken immediately after delivery in a subset of the 
 Western Australian Pregnancy Cohort Study (N=373\; M=197\, F=176) were ass
 ayed for testosterone by liquid chromatography-mass spectrometry. Expressi
 ve vocabulary was measured at two years of age using the Language Developm
 ent Survey (LDS\; Rescorla\, 1989). A range of sociodemographic variables 
 posited to influence neurocognitive outcomes were also investigated. Findi
 ngs from this research may have implications for developmental disorders t
 hat involve poor language development.
LOCATION:Margaret Lowenfeld Room\, Brookside clinic\, Trumpington road
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