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SUMMARY:Microglia: Special Award for Best Supporting Actor - Dr Rosa Paoli
 celli\, Mouse Biology Unit\, European Molecular Biology Laboratory (EMBL) 
 Monterotondo\, ITALY
DTSTART:20120201T120000Z
DTEND:20120201T130000Z
UID:TALK35185@talks.cam.ac.uk
CONTACT:Shannon Tinley-Browne
DESCRIPTION:Microglia are the resident macrophages of the brain and provid
 e a surveillance and scavenging function. However\, although microglia hav
 e been shown to engulf and clear damaged cellular debris after brain insul
 t\, it remains less clear what role these cells play in the uninjured brai
 n. New evidence show that microglia actively engulf synaptic material and 
 play a major role in synaptic pruning during postnatal development in mice
 . These findings support a crucial role for microglia in synaptic and neur
 al circuit maturation and suggest that deficits in their function may cont
 ribute to synaptic abnormalities seen in some neurodevelopmental disorders
 .
LOCATION:Brain Repair Centre\, Forvie Site\, Robinson Way
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