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SUMMARY:A 2020 vision of Biology: the present and future of microscopy-bas
 ed functional genomics - Rafael Carazo-Salas
DTSTART:20120315T190000Z
DTEND:20120315T203000Z
UID:TALK35525@talks.cam.ac.uk
CONTACT:20329
DESCRIPTION:Key scientific advances that have taken place over the last de
 cade and a half – including the development of Green Fluorescent Protein
  (GFP) technologies to quantitatively and spatiotemporally dissect biologi
 cal mechanisms\, the genome sequencing of major model organisms including 
 humans\, and the development of tools to selectively silence gene expressi
 on in cells in a genome-wide fashion – have opened rich and unexpected r
 esearch avenues of biological research.\n\nIn particular\, the ensuing dev
 elopment of high-throughput microscopy-based functional genomics technolog
 ies promises to identify and clarify the function of macromolecules with u
 nparalleled resolution in their native environment in cells\, bringing us 
 closer to understanding how genotype engenders phenotype.\n\nIn this talk\
 , I will summarize recent advances in this field and use them to illustrat
 e how those advances have led to progress in our understanding of cell bio
 logy - with an emphasis on cellular morphogenesis - and how they may inspi
 re future therapeutic strategies to combat or diagnose disease. 
LOCATION:Plant Sciences Lecture Theatre\, Downing Site
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