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SUMMARY:Brain imaging in dementias—we report what we see but is what we 
 see the truth? - Peter Nestor (Department of Clinical Neurosciences\, Univ
 ersity of Cambridge)
DTSTART:20120223T151500Z
DTEND:20120223T154500Z
UID:TALK36138@talks.cam.ac.uk
CONTACT:Carola-Bibiane Schoenlieb
DESCRIPTION:Imaging technology has reached a stage of sophistication where
  it can be applied to address mechanistic questions in dementias. For inst
 ance\, structure\, neural connectivity\, metabolism\, receptor populations
  and even pathological deposits can now be imaging non-invasively. This of
 fers the potential to understand both the spatial and temporal relationshi
 ps of the various elements (e.g. cell loss\, toxic deposition of proteins 
 etc.) of these diseases with the potential to therefore tease out causal r
 elationships between pathology and neural degeneration. There are\, howeve
 r\, considerable methodological challenges. Different imaging techniques h
 ave differing signal-to-noise ratios\; furthermore errors in image process
 ing such as tissue segmentation or delineating boundaries can lead to both
  failures in detection of change and/or identification of spurious relatio
 nships. This presentation will highlight some of the problems with particu
 lar reference to processing imaging data.\n\nThe slides of this talk are o
 nline at http://www.damtp.cam.ac.uk/user/cbs31/MI_Cambridge/MathAndInfo_Ne
 twork_files/peternestortalk.pdf
LOCATION:MR2\, CMS\, Wilberforce Road\, Cambridge\, CB3 0WB
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