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SUMMARY:Mapping Neural Networks in the Fly - Gregory Jefferis\, MRC Labora
 tory of Molecular Biology (LMB)
DTSTART:20111213T110000Z
DTEND:20111213T120000Z
UID:TALK37478@talks.cam.ac.uk
CONTACT:Mikail Rubinov
DESCRIPTION:My lab studies the processing of odours in the fruit fly. We a
 re trying to understand how raw sensory information is transformed into a 
 representation that can trigger appropriate behaviour. We are combining in
  vivo electrophysiology with detailed neuroanatomical work to reconstruct 
 the relevant neural circuits down to the level of individual neurons. Much
  of our recent work has focussed on the circuits processing sex pheromones
 \, and particularly on sites of circuit dimorphism\; these could explain w
 hy male and female flies show different behavioural responses to the same 
 pheromone.\n\nI will provide some background for the problems that we are 
 studying and then review some of the techniques that we use for mapping. I
  will then show how we have been applying these techniques to large scale 
 data\, consisting of >100 groups of developmentally related neurons or ~16
 000 individual neurons from across the whole fly brain. These data provide
  the opportunity to examine network connectivity across the fly brain and 
 ask whether there are conserved organisational principles that span brain 
 networks studied by techniques with very different resolution.\n
LOCATION:Sir William Hardy Building on Downing Site
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