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SUMMARY:Epigenetic  Regulatory Complexes in Development and Cancer - Dr Pe
 ter Mulligan\, Harvard University
DTSTART:20120920T133000Z
DTEND:20120920T143000Z
UID:TALK39156@talks.cam.ac.uk
CONTACT:Dr Ireena Dutta
DESCRIPTION:Epigenetic regulatory factors\, including enzymes and chromati
 n binding proteins\, have been implicated in virtually every step of tumor
  progression and the majority of cancer sub-types.  Identification of the 
 complexes in which these regulators function has yielded insights into the
 ir mechanisms and the biological/cancer processes they regulate. My resear
 ch has focused primarily on the purification and characterization of compl
 exes of the epigenetic regulators SIRT1 and CDYL\, uncovering epigenetic m
 echanisms in Notch pathway regulation and suppression of oncogenic transfo
 rmation respectively.\n
LOCATION:Sackler Lecture Theatre\, CIMR\,  Level 7
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