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SUMMARY:Epigenetic reprogramming during sexual reproduction in plants - Fr
 ed Berger\, Temasek Life Sciences Laboratory\, Singapore
DTSTART:20121029T160000Z
DTEND:20121029T170000Z
UID:TALK39537@talks.cam.ac.uk
CONTACT:Elisabeth Burmeister
DESCRIPTION:DNA methylation maintains genome stability and regulates gene 
 expression. In mammals\, DNA methylation is reprogrammed in the germ line 
 from one generation to the next. In plants\, it was considered that patter
 ns of DNA methylation are stably maintained through sexual reproduction. H
 owever we now provide evidence that indicate that DNA methylation is repro
 grammed during gametogenesis and embryogenesis. Arabidopsis gametogenesis 
 is marked by reduction of DNA methylation activity. After fertilization bo
 th maintenance and de novo DNA methyltransferases are expressed strongly i
 n the embryo leading to reestablishment of DNA methylation patterns on tra
 nsposable element and acquisition of new patterns of DNA methylation. We p
 ropose that this cycle of DNA methylation enables a limited degree of repr
 ogramming of the epigenome and could participate to plant adaptability.
LOCATION:The Sainsbury Laboratory Auditorium
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