BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:TopoICE and other software tools for investigating topological pro
 blems in DNA - Scharein\, R (Hypnagogic Software\, Canada)
DTSTART:20120907T103000Z
DTEND:20120907T105000Z
UID:TALK39587@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:Mathematicians and biologists studying knotting and tangling i
 ssues in DNA can benefit from powerful interactive software tools. These c
 an be used to explore what is mathematically possibly in certain kinds of 
 reactions that DNA may undergo (crossing changes or recombination\, for ex
 ample). This information may be helpful in refining biological models or e
 ven in suggesting new experiments.  In this talk\, we will examine several
  software tools starting with the Topological Interactive Construction Eng
 ine (TopoICE). TopoICE has been available as part of the KnotPlot package 
 for several years\, in two versions: TopoICE-X (crossing changes) and Topo
 ICE-R (recombination).  Here we present these in a revamped\, extended and
  more usable form.  Also\, we introduce TopoICE-S\, intended to investigat
 e knot distances via smoothings.  This will be accompanied by newly obtain
 ed smoothing distance information. This talk will also unveil TopoICE and 
 other DNA topology tools as free standalone applications (independent of K
 notPlot) and running on mobile devices. \n\nThis is joint work with Isabel
  Darcy.\n\n\n
LOCATION:Seminar Room 1\, Newton Institute
END:VEVENT
END:VCALENDAR