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SUMMARY:Some assembly required: In vitro reconstitution of cellular struct
 ures - Professor Dan Fletcher. University of California Berkeley. 
DTSTART:20130307T160000Z
DTEND:20130307T170000Z
UID:TALK40188@talks.cam.ac.uk
CONTACT:Annabel Griffiths
DESCRIPTION:Understanding the molecular basis of cellular behavior is a ce
 ntral goal in biology and a critical guide for medical research.  Increasi
 ng knowledge of the essential proteins in a complex processes such as craw
 ling motility and cell division raises the tantalizing question:  Do we kn
 ow enough to build it?  Progress towards reconstitution of micron-scale ce
 llular structures and processes has been limited by the challenges of gene
 rating in vitro systems that capture the spatial organization\, physical c
 onstraints\, and dynamics of living cells.  This talk will describe on-goi
 ng efforts to create functional reconstitutions of cytoskeletal and membra
 ne processes involved in cellular protrusions and shape change.  The lesso
 ns of what works – and what doesn’t – are helping to guide efforts t
 o build biological systems from the bottom up.
LOCATION:Hodgkin Huxley Seminar Room\, Physiology Building\, Downing Site
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