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SUMMARY:Centrality clubs and concepts of the core: decoding the communicat
 ive organisation of brain networks - Emma Towlson\, Department of Physics 
 (Cavendish Laboratory)\, University of Cambridge
DTSTART:20121009T100000Z
DTEND:20121009T110000Z
UID:TALK40570@talks.cam.ac.uk
CONTACT:Mikail Rubinov
DESCRIPTION:There has been increasing interest in topological analysis of 
 brain networks as complex systems\, often on the basis of neuroimaging dat
 a which typically represent the large-scale organisation of nervous system
 s. We use graph theory to identify and investigate the so-called 'rich-clu
 b' phenomenon\, characterised by the presence of a densely interconnected 
 set of hub nodes\, of the neuronal connectome of the nematode C. elegans. 
 We discuss the globally integrative nature of the rich club and the trade-
 off between high wiring cost and behavioural value. Structural data on the
  human brain has already found evidence of such a rich-club\, which we ide
 ntify within functional networks extracted from rest state fMRI data. We g
 o on to discuss an extension to a generalised family of centrality clubs a
 nd suggest a mechanism by which to quantify the effectiveness of antipsych
 otic medication at combatting schizophrenia.\n
LOCATION:BCNI seminar room\, Sir William Hardy Building\, Downing Site
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