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SUMMARY:From the Nuts and Bolts of Synthetic Biology to Engineering New Ge
 nomes - Dr Tom Ellis
DTSTART:20121113T181500Z
DTEND:20121113T193000Z
UID:TALK40812@talks.cam.ac.uk
CONTACT:James Scott-Brown
DESCRIPTION:Synthetic biology seeks to understand and derive value from bi
 ology via its re-design and synthesis using engineering principles. Despit
 e its early stage\, synthetic biology has already shown great potential to
  make both scientific breakthroughs and yield applications. Within synthet
 ic biology are emerging areas that include re-wiring of gene regulation fo
 r novel cellular functions\, new methods for DNA synthesis and assembly\, 
 rational DNA part design and the use of mathematical modelling and softwar
 e tools to inform biological design. The one area of synthetic biology tha
 t has had the greatest impact on the public's imagination so far has been 
 genome engineering\, via the complete synthesis and operation of a cellula
 r genome in 2010 by Craig Venter and others. While this work provided a la
 ndmark moment for the subject\, we are still far away from understanding h
 ow to rationally go from a set of DNA parts to designer genomes. In this t
 alk Dr Ellis will discuss his lab’s efforts to tie-together parts-based 
 synthetic biology in yeast and genome engineering of yeast towards the end
  goal of writing custom genomes for specific applications.
LOCATION:Winstanley Lecture Theatre
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