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SUMMARY:Evolution of body axes in Eumetazoa: what can we learn from Cnidar
 ia? - Grigory Genikhovich\, University of Vienna\, Austria
DTSTART:20121205T130000Z
DTEND:20121205T140000Z
UID:TALK40914@talks.cam.ac.uk
CONTACT:Vera Hunnekuhl
DESCRIPTION:Evolution of body axes in Eumetazoa: what\ncan we learn from C
 nidaria?\n\nIt has been suggested that Wnt signaling established the prima
 ry\nanterior-posterior body axis\, and BMP signaling defined the secondary
 \ndorso-ventral body axis in the last common ancestor of Bilateria. The\np
 hylum Cnidaria\, a sister group of the Bilateria\, includes mostly\nradial
 ly symmetric animals like jellyfish and hydroids. Additionally\, it\nconta
 ins its own class of bilaterally symmetric animals\, the Anthozoa\n(corals
 \, sea anemones). Apart from the main oral-aboral axis common to\nall cnid
 arians\, the anthozoans have a secondary "directive" axis\northogonal to t
 he primary one. Strikingly\, like in Bilateria\, the\nprimary oral-aboral 
 axis is specified by Wnt signaling\, and BMP\nsignaling is involved in def
 ining the secondary directive axis in a sea\nanemone /Nematostella vectens
 is/. This adds to the long-standing debate\nwhether any of the cnidarian b
 ody axes are homologous to any of the\nbilaterian ones. I will address the
  question of how the body axes are\nestablished in /Nematostella vectensis
 / and if any of the cnidarian body\naxes are homologous to any of the bila
 terian ones.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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